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Enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway diagrams of downregulated differentially expressed genes between semen- and sham-inseminated birds at late lay. KEGG pathway diagrams illustrate downregulation of genes in the ribosome (A) ribosome biogenesis (B) , proteasome (C) pathways in the semen group at late lay. Fold-change (log2) cutoff in color code: bright red indicates most upregulated, bright green, most downregulated.

Journal: Frontiers in Physiology

Article Title: Prolonged repeated inseminations trigger a local immune response and accelerate aging of the uterovaginal junction in turkey hens

doi: 10.3389/fphys.2023.1275922

Figure Lengend Snippet: Enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway diagrams of downregulated differentially expressed genes between semen- and sham-inseminated birds at late lay. KEGG pathway diagrams illustrate downregulation of genes in the ribosome (A) ribosome biogenesis (B) , proteasome (C) pathways in the semen group at late lay. Fold-change (log2) cutoff in color code: bright red indicates most upregulated, bright green, most downregulated.

Article Snippet: KEGG pathway diagrams ( ) were used to visualize gene expression data using Pathview ( ).

Techniques:

Enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of upregulated differentially expressed genes between semen- and sham-inseminated birds at late lay. KEGG pathway diagrams illustrate upregulation of genes in the C-type lectin receptor signaling (A) and extracellular matrix (ECM)-receptor interaction (B) pathways in the semen group at late lay. Fold-change (log2) cutoff in color code: bright red indicates most upregulated, bright green, most downregulated.

Journal: Frontiers in Physiology

Article Title: Prolonged repeated inseminations trigger a local immune response and accelerate aging of the uterovaginal junction in turkey hens

doi: 10.3389/fphys.2023.1275922

Figure Lengend Snippet: Enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of upregulated differentially expressed genes between semen- and sham-inseminated birds at late lay. KEGG pathway diagrams illustrate upregulation of genes in the C-type lectin receptor signaling (A) and extracellular matrix (ECM)-receptor interaction (B) pathways in the semen group at late lay. Fold-change (log2) cutoff in color code: bright red indicates most upregulated, bright green, most downregulated.

Article Snippet: KEGG pathway diagrams ( ) were used to visualize gene expression data using Pathview ( ).

Techniques:

KEGG pathway enrichment analysis of DEGs. (A) Pathways enriched among down-regulated DEGs. The antigen processing and presentation pathway is highlighted. (B) The single pathway enriched among up-regulated DEGs. (C) Diagram of the KEGG “antigen processing and presentation” pathway. Red stars indicate genes that are down-regulated in microglia grown on SPI-collagen. Note that the number of stars is not equal to the number of DEGs because some boxes (e.g. MHCII) represent multiple genes and others such as Ii, SLIP and CLIP are proteolytic products of a single protein. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)

Journal: Heliyon

Article Title: Transcriptomic analysis reveals the immune response of human microglia to a soy protein and collagen hybrid bioscaffold

doi: 10.1016/j.heliyon.2023.e13352

Figure Lengend Snippet: KEGG pathway enrichment analysis of DEGs. (A) Pathways enriched among down-regulated DEGs. The antigen processing and presentation pathway is highlighted. (B) The single pathway enriched among up-regulated DEGs. (C) Diagram of the KEGG “antigen processing and presentation” pathway. Red stars indicate genes that are down-regulated in microglia grown on SPI-collagen. Note that the number of stars is not equal to the number of DEGs because some boxes (e.g. MHCII) represent multiple genes and others such as Ii, SLIP and CLIP are proteolytic products of a single protein. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)

Article Snippet: The annotated KEGG pathway diagram was produced using Pathview [ ].

Techniques: